Studies & Related Articles

1.0 T vs 7 T – When Low Field is Better

 

By Silvio Aime, Ph.D. Head, NMR Laboratory, Department of Chemistry University of Turino, Italy

Compact MRI at 1 Tesla has many advantages over high-field superconducting MRI; in particular, a key imaging benefit is the increased sensitivity for gadolinium-based contrast imaging.

In a recent paper, “MRI of cells and mice at 1 and 7 Tesla with Gd‐targeting agents: when the low field is better!”  the researchers concluded that “for slowly moving Gd complexes, it is possible to obtain in vivo sensitivity enhancements at 1T several times higher than that attained at high fields.”

The reported results indicate that, for applications in which the paramagnetic agent is bound to a macromolecular system in slow‐moving conditions, a high‐resolution 1 T scanner is preferable to a high‐field one. The availability of low cost, easy-to-use 1T MRI scanners may markedly increase the number of biological groups that should come to consider in vivo MRI as a complementary or alternative tool to other imaging modalities.

Click below to download the full paper.

ARTICLES

ARTICLE 

Simultaneous Multiparametric PET/MRI with Silicon Photomultiplier PET and Ultra-High-Field MRI for Small Animal Imaging

ARTICLE 

Select Listing of Scientific Papers and Posters Citing M-Series Compact MRI Systems

ARTICLE 

MRI as a Noninvasive Method for Longitudinal Monitoring of Infusion Site Reactions Following Administration of a Novel Apomorphone Formulation

ABSTRACTS

ABSTRACT

Compact Magentic Resonance Imaging Systems -- Novel Cost-Effective Tools for Preclinical Drug Safety and Efficacy Evaluation

ABSTRACT

Practical Applications of in Vivo and ex Vivo MRI in Toxicologic Pathology using a Novel High-Performance Compact MRI System

REGULATORY FORUM

Imaging Applications in Toxicologic Pathology - Recommendations for Use in Regulated Nonclinical Toxicity Studies

POSTERS

SCIENTIFIC PAPERS & POSTERS

Compact Magentic Resonance Imaging Systems -- Novel Cost-Effective Tools for Preclinical Drug Safety and Efficacy Evaluation

POSTER

Compact MRI for the Detection of Teratoma Development Following Intrathecal Human Embryonic Stem Cells Injection in NOD-SCID Mice

POSTER

Initial In Vivo Imaging Studies Using Multi-Parametric Simultaneous PET/MRI imager